Dexmedetomidine
™ Precedex
4 mcg/ml
Mild Sedation
0.2 mcg/kg/hr
15-30 min to full effect
Moderate Sedation
LD: 0.5 mcg/kg x 10 min
MD: 0.3 mcg/kg/hr
20-25 min to full effect
Procedural Sedation
LD: 1 mcg/kg x 10 min
MD: 0.6 mcg/kg/hr
Range:
0.2-1.0 mcg/kg/hr
Fiberoptic Intubation
LD: 1 mcg/kg
MD: 0.7 mcg/kg/min
Elederly->Lower Dose
Bradycardia:
robinul, ephedrine, atropine
t1/2 2 hours
References:
