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Strengths/Mixed: Heparin: |
1X: 100 u/ml 10X: 1000 u/ml 50X: 5000 u/ml |
Acute MI - PCI: |
ADULT: |
LD: 50-70 u/kg after Glycoprotein IIb/IIIa Target ACT 200-250 seconds LD: 70-100 u/kg no Glycoprotein IIb/IIIa Target ACT 250-300 seconds (HemoTec) or 300-350 seconds (Hemochron) LD: 60 u/kg after TPA/SK MAX 4000 units, then 12 u/kg/hr - Target aPTT 1.5-2.0 x control, MAX 48 hrs |
Atrial Fibrillation: |
ADULT: |
Thromboembolism |
BD(option 1): 10,0000 u then 5000-10,000 u/4-6 h BD(option2): 5000 u then 20,000-40,000/d |
Cardioversion |
BD: 80 u/kg, then MD: 18 u/kg/hr OR BD 5000 u, then MD 1000 u/hr |
DIC: |
ADULT: |
LD (option 1): 10,000 u then 5000-10,000 q 4-6h LD (option2): 5000 u then 20,000-40,000/24 h |
Hemodialysis: |
ADULT: |
LD: 25-30 u/kg then 1500-2000 u/hr |
Heart Operation with ECC: |
ADULT: |
LD: 150-400 u/kg, usually 300 u/kg |
Unstable Angina: |
ADULT: |
LD: 60 u/kg MAX 4000 u MD: 12 u/kg/hr - target aPTT 1.5-2.5 x control |
Venous Thromboembolism Rx: |
ADULT: |
BD(option 1): 10,0000 u then 5000-10,000 u/4-6 h |
Cancer Dx: |
BD: 80 u/kg, then MD: 18 u/kg/hr |
Precuations |
May contain Benzyl Alcohol Thrombocytopenia HIT DIC Pregnancy Severe HTN Menstration Surgery Heparin Resistance Infants < 10 kg (Dose error) Contraindication: HIT GIB Bleeding Disorder SAH SBE |
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